DUOBRII® is a combination of a steroid and a retinoid for long-term control of plaque psoriasis.

DUOBRII® is approved for plaque psoriasis in adults.

Duobrii® is a prescription lotion that helps treat plaque psoriasis by combining two powerful ingredients:
Halobetasol: A steroid that helps reduce redness, itching, and swelling.
Tazarotene: A retinoid that helps slow down skin cell growth and smooth rough patches.
Together, they help clear thick, scaly skin and keep flare-ups under control — all in one daily lotion that’s gentle enough for longer use.

Apply a thin layer of Duobrii® to the affected skin once a day.
Gently rub it in until fully absorbed.
Wash your hands after applying (unless treating your hands).
Use only on the skin. Do not use on the face, groin, or underarms unless your doctor says it’s okay.
Reminder: Follow your prescriber’s directions, as your treatment plan may vary.
Indication:
Plaque psoriasis in adults.
Important patient information:
Tell your healthcare provider about any allergies, current medications, skin conditions, or if you are pregnant or breastfeeding before using this medication.
Possible side effects:
May include redness, dryness, irritation, or allergic reaction. More serious reactions are rare but possible. Stop use and seek medical advice if you experience severe discomfort, rash, swelling, or difficulty breathing.
Refer to the full Prescribing Information and Patient Information.

